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More Gene Mutations Linked to Autism Risk

26 Jun 2009 –  More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from the University of Pennsylvania School of Medicine, The Children’s Hospital of Philadelphia (CHOP), and several collaborating institutions. This study identified 27... Read more

Trio of Signals Induces Liver and Pancreas Cell Development in the Embryo

25 Jun 2009 –  Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated cells, researchers hope to one day fill the acute shortage in pancreatic and... Read more

Penn Muscle Institute Researchers Awarded $6.7 Million from NIH to Study Molecular Motors

24 Jun 2009 –  University of Pennsylvania School of Medicine scientists have been awarded $6.7 million from the National Institute of General Medical Sciences to investigate the role of molecular motors in cell biology. With this grant, the researchers will continue their studies of cytoskeletal motors that... Read more

Appetite-Stimulating Hormone is First Potential Medical Treatment for Frailty in Older Women

17 Jun 2009 –  Older women suffering from clinical frailty stand to benefit from the first potential medical treatment for the condition, according to a study presented last week by Penn Medicine researchers at ENDO, The Endocrine Society’s 91st Annual Meeting. Ghrelin, a hormone that stimulates appetite, was... Read more

Protein Structures from the Human Immune System’s Oldest Branch Shed Light on a Range of Diseases

17 Jun 2009 –  Researchers have determined the structure of C3 convertase and of the C3b fragment in complex with factor H. These new structures, both involving a central component of an enzyme important to the complement system of the immune response, reveal how this system fights invading microbes while avoiding... Read more

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